RESEARCH ABSTRACTS

Title: Favourable Prognosis of NPM1 Mutation may have Linkage with High Expression of HOXA and PBX3 Genes.
Authors: Ariz Akhter, Ghaleb Elyamany, Tariq Roshan, Adnan Mansoor. Cytogenetically Normal Acute Myeloid Leukaemia (CN-AML):
Abstract # 1065. S-1085. Laboratory Investigation. VOLUME 103, ISSUE 3, SUPPLEMENT , 100106, MARCH 2023.
Title: Cytogenetically Normal Acute Myeloid Leukaemia (CN-AML) in Young Adults: High Expression of ATM serine/threonine kinase (ATM) Gene has Prognostic Implications.
Authors: Hamza Kamran, Ariz Akhter, Ghaleb Elyamany, Tariq Roshan, Mansoor.
Abstract # 1030. S-1164. Laboratory Investigation. VOLUME 103, ISSUE 3, SUPPLEMENT , 100106, MARCH 2023.
Title: Exploring the Molecular Landscape of Large B-cell lymphoma of Immune privileged sites: Preliminary Insights into Phosphodiesterase 4 expression and Potential Therapeutic Directions.
Authors: Yuan Xu, Ariz Akhter, Ghaleb Elyamany, Tariq Mahmood Roshan, Adnan Mansoor.
Accepted as platform presentation at USCAP meeting 2024.
Title: Crucial Mediator of Chemoresistance and Its Interface with MAPK Pathway – A Prospective Target for Neoadjuvant Therapy.
Authors: Yuan Xu, Ariz Akhter, Ghaleb Elyamany, Tariq Mahmood Roshan, Adnan Mansoor ABCG2 Hyperexpression in Large B-Cell Lymphoma of Immune- Privileged Sites:.
USCAP meeting 2024.
Title: Cytogenetically Normal Acute Myeloid Leukaemia (CN-AML): Favourable Prognosis of NPM1 Mutation may have Linkage with High Expression of HOXA and PBX3 Genes.
Authors: Ariz Akhter1, Ghaleb Elyamany2, Tariq Roshan3, Adnan Mansoor.
Abstract # 1065. S-1085. Laboratory Investigation. Volume 103, issue 3, supplement , 100106, march 2023.
Title: Cytogenetically Normal Acute Myeloid Leukaemia (CN-AML) in Young Adults: High Expression of ATM serine/threonine kinase (ATM) Gene has Prognostic Implications.
Authors: Hamza Kamran1, Ariz Akhter1, Ghaleb Elyamany2, Tariq Roshan3,Adnan Mansoor.
Abstract # 1030. S-1164. Laboratory Investigation. Volume 103, issue 3, supplement , 100106, march 2023.
Title: Expression of CD47 Protein in Hematolymphoid Neoplasms: Implications for CD47-Mediated Cancer Immunotherapy.
Authors: Jingjing Zhang, Philip Bulterys, Sebastian Fernandez-Pol, Sheren Younes, Shuchun Zhao, Adnan Mansoor, Yasodha Natkunam.
(Abstract #971) Mod Pathol 35, 1016–1162 (2022)
Title: Prognostic Implications of NOTCH1 Pathway Activation Through Transforming GrowthFactor-B (TGF-Beta ) / SETBP1 in Childhood Acute Myeloid Leukemia (AML); Report of a Pilot Study.
Authors: Ghaleb Elyamany1, Ariz Akhter2, Hamza Kamran2, Hassan Rizwan2, Meer- Taher Shabani-Rad3, Adnan Mansoor
ABSTRACT # 682- Mod Pathol 34, 927–1049 (2021).
Title: Plasmablastic Lymphoma (PBL): Crosstalk Between Overexpressed Transforming Growth Factor Beta (TGFB ) Pathway Molecules With The Wnt/ Beta-Catenin Pathway May Identify Potential Therapeutic Targets.
Authors: Hamza Kamran, Ghaleb Elyamany, Ariz Akhter, Hassan Rizwan, Meer-Taher Shabani-Rad, Adnan Mansoor
ABSTRACT # 710- Mod Pathol 34, 927–1049 (2021).
Title : Acute Myeloid Leukaemia in Elderly: Extensive Expression Analysis of DNA Damage Response (DDR) and Anti- Apoptosis Genes Identify Novel Targets for Potential “Synergistic Lethality”. November 2020.
Authors: Hassan Rizwan, Hamza Kamran, Ariz Akhter, Ghaleb Elyamany, Meer-Taher Shahbani-Rad and Adnan Mansoor.
Blood. 136 (Supplement 1):39-39
Title : “Losing the Brakes” - Suppressed Inhibitors are Another Possible Mechanism of Uncontrolled Wnt Signaling in Old Age AML and a Potential for Targeted Therapy.
Authors:Ariz Akhter, Ghaleb Elyamany, Meer-Taher Shabani-Rad, Adnan Mansoor.
(Abstract 1321) Modern Pathology 2020; 33 (suppl 2): page 1247
Title : Wnt/β-catenin Signaling in Plasmablastic Lymphoma (PBL) Remains “In Check” through High Expression of Wnt/β-catenin Inhibitors.
Authors:Ariz Akhter, Ghaleb Elyamany, Rasha ElGamal, Meer-Taher Shabani-Rad, Adnan Mansoor.
(Abstract 1320) Modern Pathology 2020; 33 (suppl 2): page 1246.
Title :Canadian Harmonization of Hans’ Algorithm for Diffuse Large B-Cell Lymphoma (DLBCL); Aligning Analytical Sensitivity with Pathologist's Readout Significantly Improves Diagnostic Accuracy
Authors:Emina Torlakovic, Ariz Akhter, Muhamad Sadek Almiski, Philip Berardi, Carol Cheung, Jean Desch nes, Rasha ElGamal, Pedro Farinha, Antonio Maietta, Brian Olsen, Catherine Ross, H. Rommel Seno, Allam Shawwa, Monalisa Sur, Adnan Mansoor.
(Abstract 1482) Modern Pathology 2020; 33 (suppl 2): page 1398-1399
Title :Differential Expression of Immunity Related Genes Can Predict Moderate-Severe Chronic GvHD Early after Myeloblative Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation.
Authors:Amit Kalra, Poonam Dharmani-Khan, Stuti Patel, Rehan Mujeeb Faridi, Victor Lewis, Andrew Daly, Adnan Mansoor, Meer-Taher Shabani-Rad, Jan Storek, Faisal M Khan;
2019 Mar 01;25(3 suppl):S237
Title : Differential expression of DNA damage response (DDR) genes between Follicular lymphoma (FL) and Diffuse Large B-cell Lymphoma (DLCBL).
Authors:Ariz Akhter, Adnan Mansoor, Etienne Mahe, Meer-Taher Shabani-Rad, Carolyn Owen, Douglas Stewart;
(Abstract #1237) Modern Pathology. 2019 mar 01;32(Suppl 2):3.
Title : Un-regulation of the MYD88 Toll-like receptor B-cell receptor (MY-T-BCR) Super complex and mTOR Signaling Axis in Primary Testicular Diffuse Large B-cell Lymphoma.
Authors:Jeffrey Tompkins, Ariz Akhter, Kiril Trpkov, Asli Yilmaz, Meer-Taher Shabani- Rad, Carolyn Owen, Douglas Stewart, Adnan Mansoor;
(Abstract #1402) Modern Pathology. 2019 Mar 18;32(Suppl 2):151
Title : Early Predictions of Moderate-Severe Chronic GvHD by Immunity Related Transcriptome. American Society of Hematology 2018 Annual Meeting – for oral presentation.
Authors:Amit Kalra, Poonam Dharmani-Khan, Stuti Patel, Rehan Mujeeb Faridi, Victor Lewis, Andrew Daly, Adnan Mansoor, Meer-Taher Shabani-Rad, Jan Storek, Faisal M Khan;
Title : Deficiency of Adenosine Deaminase 2 (DADA2) Presenting As Familial Hodgkin Lymphoma.
Authors:Fahad Alabbas, Omar Alsharief, Isabelle Meyts, Fatma Albatniji, Michael Hershfield, Adnan Mansoor, Ghaleb Elyamany;
Blood 2018 Nov 21;132(Suppl):5373